Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21251395 | 0.87 | — | — | |
| SCHEMBL12643318 | 0.87 | — | — | |
| SCHEMBL26305313 | 0.87 | CA2 (0.32) | — | |
| SCHEMBL1682464 | 0.82 | — | — | |
| SCHEMBL9375683 | 0.81 | — | — | |
| SCHEMBL7688091 | 0.79 | — | — | |
| SCHEMBL27947117 | 0.79 | — | — | |
| SCHEMBL620407 | 0.75 | HSD17B10 (0.52) | MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL7685539 | 0.75 | — | — | |
| Ethylene Glycol SCHEMBL9377213 | 0.73 | TSHR (0.33) | MEN1KMT2ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046008-A2 | MATERIALS AND METHODS FOR INCREASING HSP20 ACTIVITY | THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2012-04-12 | — | — | WO | disclosed |