Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746442 | 0.92 | HSD17B10 (0.48) | HSD17B10TDP1MAPK1LMNA | |
| SCHEMBL10341684 | 0.92 | HSD17B10 (0.48) | HSD17B10TDP1MAPK1LMNA | |
| SCHEMBL23466902 | 0.90 | HSD17B10 (0.47) | HSD17B10TDP1MAPK1 | |
| SCHEMBL619721 | 0.89 | — | — | |
| SCHEMBL19762340 | 0.83 | HSD17B10 (0.52) | HSD17B10TDP1MAPK1MEN1KMT2A | |
| SCHEMBL6555797 | 0.81 | HSD17B10 (0.74) | HSD17B10TDP1MAPK1LMNAMEN1 | |
| SCHEMBL170070 | 0.78 | HSD17B10 (0.70) | HSD17B10TDP1MAPK1LMNAMEN1 | |
| SCHEMBL10071804 | 0.75 | MEN1 (0.37) | HSD17B10MAPK1MEN1KMT2A | |
| SCHEMBL23291323 | 0.75 | HSD17B10 (0.58) | HSD17B10TDP1MAPK1LMNAMEN1 | |
| SCHEMBL1344543 | 0.74 | HSD17B10 (0.64) | HSD17B10TDP1MAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245003-A2 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-11-03 | — | — | EP | claimed |
| WO-2009106552-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-09-03 | — | — | WO | claimed |
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | claimed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | claimed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | claimed |
| US-8535642-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2013-09-17 | — | — | US | disclosed |
| US-20120039815-A9 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-02-16 | — | — | US | disclosed |
| US-20110052504-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-03-03 | — | — | US | disclosed |
| EP-2245003-A2 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010060941-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-06-03 | — | — | WO | disclosed |
| WO-2009106552-A2 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-09-03 | — | — | WO | disclosed |
| EP-0173748-B1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4663478-A | Process for producing a para-substituted phenol derivative | Hirai, Hidefuni | 1987-05-05 | — | — | US | disclosed |
| EP-0173748-A1 | PROCESS FOR PRODUCING SUBSTITUTED UNSATURATED SIX-MEMBERED RING COMPOUNDS FROM PHENOL DERIVATIVES | HIRAI, Hidefumi (JP) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120039815-A9 | CONTRAST AGENTS | C5, TXN, CBR3 | HSD17B10 3339/4885TDP1 4659/4885MAPK1 1462/4885 |
| US-20110052504-A1 | CONTRAST AGENTS | C5, TXN, CBR3 | HSD17B10 3339/4885TDP1 4659/4885MAPK1 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.