SCHEMBL10072075

SCHEMBL10072075

Cc1ccc(N(c2ccc(C)cc2)c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
MAPT P10636 3/20 0.42
PABPC1 P11940 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CRHBP P24387 2/20 0.42
CRHR2 Q13324 2/20 0.42
KEAP1 Q14145 2/20 0.42
NFE2L2 Q16236 2/20 0.42
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
POLB P06746 1/20 0.40
USP2 O75604 3/20 0.39
ALDH1A1 P00352 7/20 0.38
HPGD P15428 3/20 0.38
GAA P10253 2/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 4/20 0.37
CASP1 P29466 3/20 0.37
TSHR P16473 3/20 0.37
MAPK1 P28482 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10128557 0.97 KDM4E (0.41) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL14010644 0.95 KDM4E (0.40) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL18037044 0.91 KDM4E (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL29597568 0.91 KDM4E (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL14010652 0.91 KDM4E (0.40) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL7619293 0.91 KDM4E (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL14262596 0.91 MEN1 (0.36) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL12292427 0.90 MAPT (0.39) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL13832170 0.89 CYP2A6 (0.38) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL13832166 0.88 KDM4E (0.43) KDM4EMAPTPABPC1SMN1; SMN2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012153083-A1 LIGHT EMITTING MATERIAL, COMPOSITION AND DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-11-15 WO disclosed
US-8304096-B2 Fused polycyclic aromatic compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2012-11-06 US disclosed
US-8304096-B2 Fused polycyclic aromatic compound and organic light emitting device using the compound CANON KABUSHIKI KAISHA (JP) 2012-11-06 US disclosed
EP-1412450-B1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORP (JP) 2012-02-29 EP disclosed
US-20110095284-A1 FUSED POLYCYCLIC AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-04-28 US disclosed
US-20110095284-A1 FUSED POLYCYCLIC AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-04-28 US disclosed
US-7733012-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2010-06-08 US disclosed
US-7733012-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2010-06-08 US disclosed
WO-2010008034-A1 FUSED POLYCYCLIC AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND CANON KABUSHIKI KAISHA (JP) 2010-01-21 WO disclosed
US-7517592-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2009-04-14 US disclosed
US-7517592-B2 Light-emitting device and aromatic compound FUJIFILM CORPORATION (JP) 2009-04-14 US disclosed
US-20080233430-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080233430-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080152948-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-06-26 US disclosed
US-20080152948-A1 LIGHT-EMITTING DEVICE AND AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2008-06-26 US disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110095284-A1 FUSED POLYCYCLIC AROMATIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE COMPOUND AFF1, AFF2, LEF1 KDM4E 3227/4885MAPT 1353/4885PABPC1 2385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.