SCHEMBL13832166

SCHEMBL13832166

Cc1ccc(N(c2cccc3c(C)cccc23)c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
MAPT P10636 3/20 0.43
PABPC1 P11940 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2A6 P11509 3/20 0.36
CYP1A2 P05177 3/20 0.36
CRHBP P24387 2/20 0.36
CRHR2 Q13324 2/20 0.36
KEAP1 Q14145 2/20 0.36
NFE2L2 Q16236 2/20 0.36
ALDH1A1 P00352 6/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
USP2 O75604 3/20 0.36
CASP1 P29466 3/20 0.36
HSD17B10 Q99714 3/20 0.36
GAA P10253 2/20 0.36
CASP7 P55210 2/20 0.36
HBB P68871 2/20 0.36
BRCA1 P38398 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10072075 0.88 KDM4E (0.42) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL13832167 0.88 MAPT (0.50) KDM4EMAPTPABPC1SMN1; SMN2CYP2A6
SCHEMBL10128557 0.85 KDM4E (0.41) KDM4EMAPTPABPC1SMN1; SMN2CYP1A2
SCHEMBL14010642 0.84 MAPT (0.41) KDM4EMAPTPABPC1SMN1; SMN2CYP2A6
SCHEMBL14010644 0.84 KDM4E (0.40) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL13832169 0.84 MAPT (0.56) KDM4EMAPTPABPC1SMN1; SMN2CYP2A6
SCHEMBL14010652 0.83 KDM4E (0.40) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL14197031 0.81 CYP1A2 (0.39) KDM4EMAPTPABPC1SMN1; SMN2CYP2A6
SCHEMBL7619293 0.81 KDM4E (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL18037044 0.81 KDM4E (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012153083-A1 LIGHT EMITTING MATERIAL, COMPOSITION AND DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-11-15 WO disclosed