SCHEMBL10072214

SCHEMBL10072214

CCOC(C)OCCc1ccc(N(c2ccc(C=C(c3ccc(CC)cc3)c3ccc(CC)cc3)cc2)c2ccc(CCOC(C)OCC)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
CYP2D6 P10635 1/20 0.32
MAOB P27338 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279023 0.93 KDM4E (0.30) KDM4EALDH1A1MAPTHPGD
SCHEMBL279279 0.91 CYP2D6 (0.39) KDM4EALDH1A1MAPTHPGDCYP2D6
SCHEMBL279018 0.80 PTGS2 (0.39) KDM4EALDH1A1MAPTHPGDMAOB
SCHEMBL14063401 0.79 AKR1C3 (0.38) KDM4EALDH1A1MAPTHPGDCYP2D6
SCHEMBL279277 0.78 CYP2D6 (0.38) KDM4EALDH1A1MAPTHPGDCYP2D6
SCHEMBL14190104 0.76 PTGS2 (0.43) CYP2D6ESR1
SCHEMBL15038441 0.76 PTGS2 (0.49) KDM4EALDH1A1MAPTHPGDESR1
SCHEMBL15038792 0.76 PTGS2 (0.49) KDM4EALDH1A1MAPTHPGDESR1
SCHEMBL10070915 0.74 PTGS2 (0.47) ALDH1A1MAPTCYP2D6ESR1ESR2
SCHEMBL13681240 0.73 PTGS2 (0.39) KDM4EALDH1A1MAPTHPGDCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed
US-20080261135-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2008-10-23 US disclosed