Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038792 | 1.00 | PTGS2 (0.49) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL12551631 | 0.93 | PTGS2 (0.51) | PTGS2ESR1ALDH1A1MAPTHPGD | |
| SCHEMBL13508376 | 0.90 | PTGS2 (0.57) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL443217 | 0.90 | PTGS2 (0.57) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL139360 | 0.90 | PTGS2 (0.57) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL14950688 | 0.89 | PTGS2 (0.48) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL12572204 | 0.89 | PTGS2 (0.48) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL13681240 | 0.87 | PTGS2 (0.39) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL9098089 | 0.87 | PTGS2 (0.46) | PTGS2ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL14063406 | 0.86 | PTGS2 (0.41) | PTGS2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130157181-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2013-06-20 | — | — | US | disclosed |