SCHEMBL10072249

SCHEMBL10072249

C=CCOC(=O)c1ccc(C(=O)OC)c(C(=O)OCC=C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.57
ALDH1A1 P00352 10/20 0.47
HSD17B10 Q99714 5/20 0.47
TSHR P16473 2/20 0.47
KDM4E B2RXH2 13/20 0.46
HPGD P15428 5/20 0.46
MAPT P10636 3/20 0.46
ATM Q13315 2/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
SNCA P37840 1/20 0.46
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376657 0.92 CYP3A4 (0.66) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL48751 0.92 CYP3A4 (0.66) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL28854500 0.92 CYP3A4 (0.50) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL10072072 0.88 CYP3A4 (0.57) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL27528367 0.88 CYP3A4 (0.49) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
Benzene SCHEMBL9554798 0.87 CYP3A4 (0.63) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
Acrylic Acid SCHEMBL2215810 0.87 CYP3A4 (0.58) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL4570283 0.86 CYP3A4 (0.59) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL9247117 0.83 CYP3A4 (0.57) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL5366925 0.83 CYP3A4 (0.62) CYP3A4ALDH1A1HSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452993-A2 Thermosetting fluoropolyether adhesive composition and adhesion method Shin-Etsu Chemical Co., Ltd. (JP) 2012-05-16 EP disclosed