Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376657 | 0.94 | CYP3A4 (0.66) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL48751 | 0.94 | CYP3A4 (0.66) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| Benzene SCHEMBL9554798 | 0.91 | CYP3A4 (0.63) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL5366925 | 0.88 | CYP3A4 (0.62) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL10072249 | 0.87 | CYP3A4 (0.57) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL10072072 | 0.87 | CYP3A4 (0.57) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL9471198 | 0.85 | CYP3A4 (0.51) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL7195876 | 0.84 | CYP3A4 (0.53) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL30843873 | 0.84 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRHSD17B10SNCA | |
| SCHEMBL10965072 | 0.84 | CYP3A4 (0.57) | CYP3A4ALDH1A1TSHRHSD17B10SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9631056-B2 | Core-first nanoparticle formation process, nanoparticle, and composition | BRIDGESTONE CORPORATION (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20160039964-A1 | WELL DEFINED, HIGHLY CROSSLINKED NANOPARTICLES AND METHOD FOR MAKING SAME | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| US-9115222-B2 | Well defined, highly crosslinked nanoparticles and method for making same | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| EP-2370349-B1 | CORE-FIRST NANOPARTICLE FORMATION PROCESS, NANOPARTICLE, AND COMPOSITION | BRIDGESTONE CORP (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8846819-B2 | Core-first nanoparticle formation process, nanoparticle, and composition | BRIDGESTONE CORPORATION (JP) | 2014-09-30 | — | — | US | disclosed |
| US-20120132346-A1 | Core-First Nanoparticle Formation Process, Nanoparticle, And Composition | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2370349-A2 | CORE-FIRST NANOPARTICLE FORMATION PROCESS, NANOPARTICLE, AND COMPOSITION | Bridgestone Corporation (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110236686-A1 | Well Defined, Highly Crosslinked Nanoparticles And Method For Making Same | BRIDGESTONE CORPORATION (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110172364-A1 | Charged Nanoparticles And Method Of Controlling Charge | YAOHONG CHEN | 2011-07-14 | — | — | US | disclosed |
| WO-2010078320-A2 | CORE-FIRST NANOPARTICLE FORMATION PROCESS, NANOPARTICLE, AND COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2010-07-08 | — | — | WO | disclosed |