Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL4256459 | 1.00 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Tetrahydrofuran SCHEMBL3544589 | 0.98 | CYP3A4 (0.60) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Tetrahydrofuran SCHEMBL2014438 | 0.95 | CYP3A4 (0.57) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28244884 | 0.89 | CYP3A4 (0.50) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28163050 | 0.89 | CYP3A4 (0.50) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28244765 | 0.89 | CYP3A4 (0.50) | CYP3A4TDP1ESR1ESR2ALDH1A1 | |
| Dioxane SCHEMBL27471817 | 0.87 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2LMNA | |
| Oxirane SCHEMBL29388114 | 0.85 | CYP3A4 (0.71) | CYP3A4TDP1ESR1ESR2LMNA | |
| Tetrahydrofuran SCHEMBL28355034 | 0.79 | ALDH1A1 (0.36) | CYP3A4TDP1ALDH1A1LMNASMN1; SMN2 | |
| Cyclohexane SCHEMBL28199422 | 0.79 | CYP3A4 (0.80) | CYP3A4TDP1ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270063-B1 | PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION | ZEON CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-9243098-B2 | Compound, polymer, cross-linked compound of polymer, and optical element including cross-linked compound | CANON KABUSHIKI KAISHA (JP) | 2016-01-26 | — | — | US | disclosed |
| US-20140163175-A1 | NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2014-06-12 | — | — | US | disclosed |
| EP-1197509-B1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | ZEON CORP (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-2270063-A2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | NIPPON ZEON CO., LTD. (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-6908970-B2 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION (JP) | 2005-06-21 | — | — | US | disclosed |
| US-20030050406-A1 | Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization | ZEON CORPORATION | 2003-03-13 | — | — | US | disclosed |
| EP-1197509-A1 | PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN | Nippon Zeon Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163175-A1 | NOVEL COMPOUND, POLYMER, CROSS-LINKED COMPOUND OF POLYMER, AND OPTICAL ELEMENT INCLUDING CROSS-LINKED COMPOUND | PCLAF, PCNA, SMC2 | CYP3A4 3992/4885TDP1 4354/4885ESR1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.