SCHEMBL10072387

SCHEMBL10072387

CCCCCCCC1(CC[C@@H]2C(C/C=C\CCCC(=O)O)C(O)C[C@H]2O)OCCO1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TBXA2R P21731 9/20 0.53
▸ ALDH1A1 P00352 3/20 0.53
▸ LMNA P02545 3/20 0.53
▸ PTGFR P43088 3/20 0.53
▸ SLCO2A1 Q92959 3/20 0.53
▸ PTGER1 P34995 2/20 0.53
▸ PTGER3 P43115 2/20 0.53
▸ PTGER4 P35408 1/20 0.53
▸ PTGDR Q13258 1/20 0.53
▸ PGR P06401 1/20 0.49
▸ ADORA3 P0DMS8 1/20 0.49
▸ ADRA2C P18825 1/20 0.49
▸ SLC6A2 P23975 1/20 0.49
▸ HTR2B P41595 1/20 0.49
▸ MC3R P41968 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49
▸ PDE4D Q08499 1/20 0.49
▸ SCN5A Q14524 1/20 0.49
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696531 1.00 TBXA2R (0.53) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL5114583 1.00 TBXA2R (0.53) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL11837676 0.99 TBXA2R (0.54) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL7615146 0.97 LMNA (0.50) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL10071927 0.96 TBXA2R (0.52) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL13587661 0.96 TBXA2R (0.52) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL1696517 0.96 TBXA2R (0.52) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL15960983 0.89 ALDH1A1 (0.55) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL1696535 0.88 PDE4D (0.53) TBXA2RALDH1A1LMNAPTGFRSLCO2A1
SCHEMBL10072381 0.88 PDE4D (0.53) TBXA2RALDH1A1LMNAPTGFRSLCO2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120088823-A1 COMPOSITION AND METHOD FOR SCALP AND HAIR TREATMENT R-TECH UENO, LTD. (JP) 2012-04-12 — — US disclosed
US-20070298134-A1 Composition and Method for Scalp and Hair Treatment R-TECH UENO, LTD. (JP) 2007-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298134-A1 Composition and Method for Scalp and Hair Treatment PTGER3, PTGDR2, HSD3B2 TBXA2R 2683/4885ALDH1A1 2791/4885LMNA 3494/4885
US-20120088823-A1 COMPOSITION AND METHOD FOR SCALP AND HAIR TREATMENT PTGER3, PTGDR2, HSD3B2 TBXA2R 2683/4885ALDH1A1 2791/4885LMNA 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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