⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179273 | 0.78 | — | — | |
| SCHEMBL6176004 | 0.78 | — | — | |
| SCHEMBL6175615 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL14991554 | 0.74 | — | — | |
| SCHEMBL6178476 | 0.74 | ADRB2 (0.35) | — | |
| SCHEMBL1562061 | 0.73 | — | — | |
| SCHEMBL12226 | 0.73 | — | — | |
| SCHEMBL7709730 | 0.70 | — | — | |
| Ethoxycarbonyl Group SCHEMBL3383091 | 0.70 | — | — | |
| SCHEMBL29011891 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992363-B1 | TRANSDERMAL ABSORPTION PREPARATION | HISAMITSU PHARMACEUTICAL CO (JP) | 2012-12-19 | — | — | EP | claimed |
| CN-102026664-A | Composition of stabilized beta blocker and percutaneous absorption preparation containing the same | TEIKOKU SEIYAKU KK | 2011-04-20 | — | — | CN | claimed |
| EP-2269653-A1 | COMPOSITION FOR STABILIZING -BLOCKER, AND TRANSDERMALLY ABSORBABLE PREPARATION COMPRISING THE COMPOSITION | Teikoku Seiyaku Co., Ltd. (JP) | 2011-01-05 | — | — | EP | claimed |
| US-20110104247-A1 | COMPOSITION FOR STABILIZING BETA-BLOCKER AND TRANSDERMALLY ABSORBABLE PREPARATION COMPRISING THE SAME | TEIKOKU SEIYAKU CO., LTD. (JP) | 2011-05-05 | — | — | US | disclosed |
| CN-102026664-A | Composition of stabilized beta blocker and percutaneous absorption preparation containing the same | TEIKOKU SEIYAKU KK | 2011-04-20 | — | — | CN | disclosed |
| EP-2269653-A1 | COMPOSITION FOR STABILIZING -BLOCKER, AND TRANSDERMALLY ABSORBABLE PREPARATION COMPRISING THE COMPOSITION | Teikoku Seiyaku Co., Ltd. (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| CN-1140528-C | Process for preparing herbicidal derivatives | �����ɷ� | 2004-03-03 | — | — | CN | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6552187-B1 | Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity | SYNGENTA CROP PROTECTION, INC. | 2003-04-22 | — | — | US | disclosed |
| CN-1355806-A | Process for preparation of herbicidal derivatives | SYNGENA PARTICIPATIONS AG (CH) | 2002-06-26 | — | — | CN | disclosed |
| EP-1185506-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARATION OF HERBICIDES | Syngenta Participations AG (CH) | 2002-03-13 | — | — | EP | disclosed |
| EP-1183317-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| WO-2000078712-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARTION OF HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |