SCHEMBL10072720

SCHEMBL10072720

Cc1c2ccccc2cc2ccncc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 2/20 0.55
KDM4E B2RXH2 3/20 0.55
HTT P42858 2/20 0.55
POLB P06746 2/20 0.55
RAD52 P43351 1/20 0.55
NCOA3 Q9Y6Q9 1/20 0.50
TNF P01375 1/20 0.46
CYP11B1 P15538 1/20 0.44
CYP2A6 P11509 3/20 0.44
MAOA P21397 2/20 0.43
CYP1A2 P05177 4/20 0.42
TSHR P16473 3/20 0.42
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
CASP1 P29466 2/20 0.41
RAB9A P51151 2/20 0.41
CASP7 P55210 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13707396 0.90 TOP2A (0.46) TOP2AKDM4EHTTPOLBRAD52
SCHEMBL119090 0.82 CYP1A2 (0.56) KDM4ECYP2A6MAOACYP1A2TSHR
SCHEMBL29360084 0.82 CYP1A2 (0.56) KDM4ECYP2A6MAOACYP1A2TSHR
Hydrochloric Acid SCHEMBL27879112 0.80 CYP1A2 (0.54) KDM4ECYP2A6MAOACYP1A2TSHR
Hydrogen Sulfide SCHEMBL27306888 0.80 CYP1A2 (0.54) KDM4ECYP2A6MAOACYP1A2TSHR
Ammonia Solution, Strong SCHEMBL28178967 0.80 CYP1A2 (0.54) KDM4ECYP2A6MAOACYP1A2TSHR
SCHEMBL1102485 0.79 KDM4E (0.59) TOP2AKDM4EHTTPOLBRAD52
SCHEMBL12887711 0.78 KDM4E (0.53) TOP2AKDM4EHTTPOLBRAD52
SCHEMBL13445401 0.78 KDM4E (0.53) TOP2AKDM4EHTTPOLBRAD52
SCHEMBL30641851 0.78 KDM4E (0.53) TOP2AKDM4EHTTPOLBRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223810-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-07-14 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-25 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 TOP2A 4020/4885KDM4E 4170/4885HTT 2470/4885
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOC2, SCO2, C1S TOP2A 4596/4885KDM4E 4319/4885HTT 1720/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A TOP2A 4087/4885KDM4E 4138/4885HTT 4013/4885
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 TOP2A 3530/4885KDM4E 3298/4885HTT 3566/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 TOP2A 4551/4885KDM4E 3367/4885HTT 4390/4885
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 TOP2A 3370/4885KDM4E 3009/4885HTT 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.