Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133128 | 0.81 | ALDH1A1 (0.50) | KDM4EACHEMAOAMAPTALOX5 | |
| Benzene SCHEMBL4082384 | 0.79 | ALDH1A1 (0.50) | KDM4EACHEMAOAMAPTALOX5 | |
| SCHEMBL10072720 | 0.78 | TOP2A (0.55) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL12887711 | 0.77 | KDM4E (0.53) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL30641851 | 0.77 | KDM4E (0.53) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL27110267 | 0.76 | KDM4E (0.43) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL1102619 | 0.74 | KDM4E (0.50) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL12887710 | 0.74 | TNF (0.54) | KDM4EHTTPOLBRAD52NCOA3 | |
| SCHEMBL2222268 | 0.74 | ALDH1A1 (0.55) | KDM4EACHEMAOA | |
| SCHEMBL26467980 | 0.74 | CYP1A2 (0.43) | KDM4EACHEMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161320-A2 | Fluorene derivatives and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2010-03-10 | — | — | EP | disclosed |