Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688249 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL14358816 | 0.83 | KEAP1 (0.58) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL14358814 | 0.83 | KEAP1 (0.58) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL687551 | 0.81 | CA1 (0.55) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL688839 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL687552 | 0.81 | CA1 (0.55) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL688840 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL688504 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL688505 | 0.79 | CA12 (0.49) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL688506 | 0.79 | CA12 (0.49) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |
| US-7737139-B2 | Sulfonic acids, their derivatives and pharmaceutical compositions containing them | DOMPE PHA.R.MA S.P.A. (IT) | 2010-06-15 | — | — | US | disclosed |