Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688728 | 1.00 | LMNA (0.43) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL687741 | 0.80 | CA12 (0.43) | LMNAADRB3KMT2ACA12CA2 | |
| SCHEMBL688675 | 0.78 | LMNA (0.45) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL687288 | 0.75 | CXCR2 (0.44) | KMT2ACA12CA2CA9ALOX15 | |
| SCHEMBL6460284 | 0.74 | KCNH2 (0.47) | LMNAKDM4EKMT2ACA12CA2 | |
| SCHEMBL687204 | 0.74 | LMNA (0.52) | LMNAKDM4EADRB2ADRB1ADRB3 | |
| SCHEMBL687784 | 0.73 | GAA (0.44) | LMNAKDM4EKMT2AMEN1CA12 | |
| SCHEMBL10072501 | 0.73 | GAA (0.44) | LMNAKDM4EKMT2AMEN1CA12 | |
| SCHEMBL10532863 | 0.71 | HPGD (0.58) | LMNAKDM4ECA12CA2CA9 | |
| SCHEMBL9624965 | 0.70 | HPGD (0.56) | LMNAKDM4ECA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606248-B1 | SULFONIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE SPA (IT) | 2012-02-29 | — | — | EP | disclosed |