Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PDE2A | O00408 | 2/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008264 | 0.84 | LMNA (0.45) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL1007907 | 0.83 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL1924374 | 0.80 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL1007511 | 0.80 | KDM4E (0.62) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL18343696 | 0.78 | KDM4E (0.61) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL1925112 | 0.78 | MAPT (0.55) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL24225890 | 0.77 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL18343698 | 0.77 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL1009507 | 0.77 | CSNK2A1 (0.67) | KDM4EHSD17B10ALDH1A1HPGDGLA | |
| SCHEMBL313181 | 0.76 | CSNK2A1 (0.56) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |