Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007907 | 0.90 | KDM4E (0.41) | LMNACSNK2A1KDM4EHSD17B10HPGD | |
| SCHEMBL1007301 | 0.84 | KDM4E (0.56) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1009507 | 0.78 | CSNK2A1 (0.67) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1924058 | 0.77 | CSNK2A1 (0.70) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1924384 | 0.77 | CDK2 (0.54) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL313181 | 0.77 | CSNK2A1 (0.56) | LMNACSNK2A1KDM4EHSD17B10HPGD | |
| SCHEMBL7458893 | 0.76 | LMNA (0.48) | LMNAKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1924374 | 0.76 | KDM4E (0.64) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1924383 | 0.75 | CSNK2A1 (0.54) | LMNACSNK2A1KDM4EHSD17B10HPGD | |
| SCHEMBL1924372 | 0.75 | KDM4E (0.61) | CSNK2A1KDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-07-17 | — | — | US | claimed |
| WO-2003053976-A1 | PIPAZOLO [1,5-a] PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR | BIOVITRUM AB (SE) | 2003-07-03 | — | — | WO | claimed |
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-2269990-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20030134862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-07-17 | — | — | US | disclosed |
| WO-2003053976-A1 | PIPAZOLO [1,5-a] PYRIMIDINE DERIVATIVES AS MODULATORS OF PPAR | BIOVITRUM AB (SE) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | LMNA 4015/4885CSNK2A1 779/4885KDM4E 3157/4885 |
| US-20030134862-A1 | Compounds | PPARG, PPARA, PPARD | LMNA 4449/4885CSNK2A1 3606/4885KDM4E 2909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.