Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007318 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL2075620 | 0.85 | DAO (0.40) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL2075619 | 0.85 | DAO (0.40) | MAPTKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1004890 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1004891 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1004702 | 0.73 | HRH3 (0.45) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1056685 | 0.72 | CYP1A2 (0.39) | KDM4EALDH1A1GLAGAAMMP2 | |
| SCHEMBL1056687 | 0.72 | CYP1A2 (0.39) | KDM4EALDH1A1GLAGAAMMP2 | |
| SCHEMBL1160540 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1003729 | 0.70 | ATM (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |