Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075620 | 1.00 | DAO (0.40) | DAOKDM5AKDM5BHCAR3GPR52 | |
| SCHEMBL1005240 | 0.86 | SRD5A2 (0.36) | DAOHCAR3HCAR2SRD5A2KDM4E | |
| SCHEMBL1005239 | 0.86 | SRD5A2 (0.36) | DAOHCAR3HCAR2SRD5A2KDM4E | |
| SCHEMBL1007319 | 0.85 | SMN1; SMN2 (0.42) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL1007318 | 0.85 | SMN1; SMN2 (0.42) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL1054865 | 0.76 | CYP1A2 (0.46) | DAOSRD5A2KDM4EHPGDHSD17B10 | |
| SCHEMBL1004097 | 0.76 | CYP1A2 (0.46) | DAOSRD5A2KDM4EHPGDHSD17B10 | |
| SCHEMBL1004098 | 0.76 | CYP1A2 (0.46) | DAOSRD5A2KDM4EHPGDHSD17B10 | |
| SCHEMBL30115707 | 0.69 | SRD5A2 (0.51) | DAOSRD5A2KDM4EHPGDHSD17B10 | |
| SCHEMBL1056685 | 0.65 | CYP1A2 (0.39) | KDM4EALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902252-B2 | Inhibitors of D-amino acid oxidase | SEPRACOR, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029737-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | DDO, DAO, ACHE | DAO 2/4885KDM5A 1098/4885KDM5B 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.