Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203832 | 1.00 | P2RY10 (0.56) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL19951694 | 1.00 | P2RY10 (0.56) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL11870732 | 1.00 | P2RY10 (0.56) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL25354441 | 0.98 | P2RY10 (0.54) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL25354445 | 0.98 | P2RY10 (0.54) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL2757451 | 0.92 | NOS3 (0.54) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL5607813 | 0.92 | NOS3 (0.54) | P2RY10HTTNOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7066377 | 0.91 | NOS3 (0.53) | P2RY10HTTNOS3NOS1NOS2 | |
| SCHEMBL13937592 | 0.85 | CES2 (0.53) | HTTUSP2PLA2G2CCES2TLR2 | |
| SCHEMBL16124670 | 0.84 | P2RY10 (0.51) | P2RY10GRIK1GRIK2GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051663-A1 | ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2012-04-26 | — | — | WO | disclosed |