Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713354 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL713355 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3454958 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL713352 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL713353 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3454962 | 1.00 | TP53 (0.38) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18614656 | 0.91 | TYR (0.41) | TP53MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18614686 | 0.90 | TYR (0.43) | TP53ALDH1A1HPGDTYRPPARG | |
| SCHEMBL18614711 | 0.90 | TYR (0.43) | TP53ALDH1A1HPGDTYRPPARG | |
| SCHEMBL20561502 | 0.90 | TYR (0.43) | TP53ALDH1A1HPGDTYRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124794-B2 | Method for the asymmetric synthesis of beta-lactone compounds | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-07-08 | — | — | US | disclosed |
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173982-A1 | NOVEL METHOD FOR THE ASYMMETRIC SYNTHESIS OF BETA-LACTONE COMPOUNDS | FASN, COASY, FADS1 | TP53 2922/4885MEN1 3603/4885KMT2A 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.