Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072974 | 1.00 | PAX8 (0.45) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL12251245 | 1.00 | PAX8 (0.45) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL14151828 | 0.92 | DPP4 (0.50) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL1036161 | 0.92 | DPP4 (0.50) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL13857686 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL23690961 | 0.79 | DPP4 (0.50) | PAX8DPP4DPP8DPP7SLC15A1 | |
| SCHEMBL13811929 | 0.78 | DPP4 (0.41) | DPP4DPP8DPP7 | |
| SCHEMBL14590394 | 0.78 | PAX8 (0.39) | PAX8DPP4CTRB1 | |
| SCHEMBL23863812 | 0.77 | CTSC (0.33) | PAX8 | |
| SCHEMBL8695992 | 0.77 | DPP4 (0.48) | PAX8DPP4DPP8DPP7CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020231-A1 | CHEMICAL LIGATION BY RING OPENING OF OXO-THIOMORPHOLINES | THE UNIVERSITY OF READING (GB) | 2012-02-16 | — | — | WO | disclosed |