Styrene

Styrene

SCHEMBL1007358

C=C.C=Cc1ccccc1.CCOCC

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TSHR P16473 1/20 0.61
RELA Q04206 1/20 0.42
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
TP53 P04637 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
NR1I2 O75469 1/20 0.38
CHRNA7 P36544 3/20 0.37
CHRNB2 P17787 2/20 0.37
CHRNB4 P30926 2/20 0.37
CHRNA3 P32297 2/20 0.37
CHRNA4 P43681 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
MAPT P10636 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1732622 0.98 ALDH1A1 (0.64) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL14917409 0.94 ALDH1A1 (0.58) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL27516896 0.94 ALDH1A1 (0.58) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL16279238 0.92 ALDH1A1 (0.56) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL9576210 0.90 ALDH1A1 (0.54) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL11646316 0.87 ALDH1A1 (0.50) ALDH1A1TSHRRELAMEN1KMT2A
Styrene SCHEMBL27272851 0.87 TSHR (0.50) ALDH1A1TSHRRELATP53ADORA3
Ether SCHEMBL28657814 0.86 ALDH1A1 (0.48) ALDH1A1TSHRRELATP53CHRNA7
Styrene SCHEMBL28034826 0.84 TSHR (0.52) ALDH1A1TSHRRELATP53ADORA3
Styrene SCHEMBL28211071 0.84 ALDH1A1 (0.78) ALDH1A1TSHRRELAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268747-A1 MODIFIED PIGMENTS HAVING REDUCED PHOSPHATE RELEASE, AND DISPERSIONS AND INKJET INK COMPOSITIONS THEREFROM Cabot Corporation (US) 2011-01-05 EP disclosed
WO-2009117071-A1 MODIFIED PIGMENTS HAVING REDUCED PHOSPHATE RELEASE, AND DISPERSIONS AND INKJET INK COMPOSITIONS THEREFROM CABOT CORPORATION (US) 2009-09-24 WO disclosed
EP-1981943-A1 INKJET INK COMPOSITIONS COMPRISING POLYMERIC DISPERSANTS HAVING ATTACHED CHROMOPHORE GROUPS Cabot Corporation (US) 2008-10-22 EP disclosed
WO-2007089859-A1 INKJET INK COMPOSITIONS COMPRISING POLYMERIC DISPERSANTS HAVING ATTACHED CHROMOPHORE GROUPS CABOT CORPORATION (US) 2007-08-09 WO disclosed