Styrene

Styrene

SCHEMBL14917409

C=Cc1ccccc1.CCOCC.CO

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TSHR P16473 2/20 0.58
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
RELA Q04206 1/20 0.41
NR1I2 O75469 1/20 0.41
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MCL1 Q07820 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1732622 0.96 ALDH1A1 (0.64) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL16279238 0.94 ALDH1A1 (0.56) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL1007358 0.94 ALDH1A1 (0.61) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL9576210 0.92 ALDH1A1 (0.54) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL27516896 0.92 ALDH1A1 (0.58) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL11646316 0.89 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL23794901 0.85 ALDH1A1 (0.50) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL11688868 0.85 ALDH1A1 (0.67) ALDH1A1TSHRMEN1KMT2ARELA
Styrene SCHEMBL6829874 0.84 ALDH1A1 (0.82) ALDH1A1TSHRTP53TDP1MAPT
Styrene SCHEMBL27887859 0.84 ALDH1A1 (0.82) ALDH1A1TSHRTP53TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016011521-A1 PROCESS FOR PRODUCING STYRENE-, METHYLSTYRENE- AND ETHYLBENZENE-FREE C6-C9 AROMATIC HYDROCARBON BLENDS AMT INTERNATIONAL INC. (US) 2016-01-28 WO disclosed
US-9067846-B2 Process for producing styrene-, methylstyrene- and ethylbenzene-free C6-C9 aromatic hydrocarbon blends AMT INTERNATIONAL INC. (US) 2015-06-30 US disclosed
US-20140364664-A1 Process for producing styrene-, methylstyrene- and ethylbenzene-free C6-C9 aromatic hydrocarbon blends CHUANG KARL TZE-TANG (CA) 2014-12-11 US disclosed
US-8766028-B2 Separating styrene from C6-C8 aromatic hydrocarbons AMT INTERNATIONAL INC. (US) 2014-07-01 US disclosed
WO-2014094105-A1 SEPARATING STYRENE FROM C6 - C8 AROMATIC HYDROCARBONS WU KUANG-YEU (US) 2014-06-26 WO disclosed
US-20130116489-A1 Separating styrene from C6 - C8 aromatic hydrocarbons CPC CORPORATION (CN) 2013-05-09 US disclosed