Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078067 | 0.82 | DPP4 (0.41) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074457 | 0.79 | DPP4 (0.41) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074326 | 0.79 | DPP4 (0.41) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074280 | 0.78 | REN (0.42) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10075001 | 0.78 | REN (0.42) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10078066 | 0.77 | REN (0.37) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10077057 | 0.76 | REN (0.36) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074292 | 0.76 | DPP4 (0.43) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074134 | 0.76 | DPP4 (0.43) | DPP4DPP8DPP7DPP9REN | |
| SCHEMBL10074293 | 0.76 | DPP4 (0.43) | DPP4DPP8DPP7DPP9REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |