SCHEMBL10074437

SCHEMBL10074437

FC1C2C3C=CC(C3)C2C1(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13123281 0.78 CYP3A4 (0.31) CYP3A4MAPT
SCHEMBL5697539 0.69 CYP3A4 (0.41) CYP3A4MAPT
SCHEMBL14494567 0.68
SCHEMBL6240119 0.64 ALDH1A1 (0.36) CYP3A4MAPT
SCHEMBL6236759 0.64 ALDH1A1 (0.36) CYP3A4MAPT
SCHEMBL1012655 0.64
SCHEMBL14494488 0.64
SCHEMBL13685018 0.61 ALDH1A1 (0.33)
SCHEMBL10034763 0.60 CYP3A4 (0.34) CYP3A4MAPT
SCHEMBL14494476 0.60 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149166-B1 PROCESS FOR FORMING AN ORGANIC LIGHT-EMITTING DIODE AND DEVICES MADE BY THE PROCESS DU PONT (US) 2012-03-21 EP disclosed