Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 12/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | FAP | Q12884 | 3/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873681 | 0.85 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6873741 | 0.85 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6877799 | 0.85 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6874198 | 0.83 | LAP3 (0.48) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL10077380 | 0.82 | LAP3 (0.42) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6873519 | 0.81 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6874066 | 0.81 | LAP3 (0.44) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6872762 | 0.81 | LAP3 (0.40) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL10074277 | 0.79 | LAP3 (0.45) | LAP3ANPEPRNPEPDNPEPDPP4 | |
| SCHEMBL6874726 | 0.78 | REN (0.41) | DPP4DPP7DPP9RENKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |