Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83968 | 0.84 | PDE1B (0.38) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL21569325 | 0.84 | PDE1B (0.39) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL29419506 | 0.83 | PDE1B (0.39) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL83557 | 0.83 | PDE1B (0.41) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL83556 | 0.83 | PDE1B (0.41) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL394833 | 0.83 | PDE1B (0.41) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL29368774 | 0.83 | PDE1B (0.41) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL394832 | 0.83 | PDE1B (0.41) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL28854494 | 0.83 | PDE1B (0.39) | ACACBPDE1BLMNANPSR1HSD17B10 | |
| SCHEMBL10074499 | 0.80 | ACACB (0.44) | ACACBCACNA2D1LMNANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299245-B2 | Method for producing pyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8101753-B2 | Production method of pyrimidine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090111984-A1 | Novel Method For Producing Pyrimidine Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111984-A1 | Novel Method For Producing Pyrimidine Compound | DPYD, UMPS, TYMP | ACACB 2155/4885PDE1B 1991/4885CACNA2D1 723/4885 |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | ACACB 426/4885PDE1B 3670/4885CACNA2D1 3928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.