Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 16/20 | 0.37 |
| ▸ | TYMS | P04818 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074515 | 0.90 | KDM4E (0.41) | KDM4EDHODH | |
| SCHEMBL10074507 | 0.90 | KDM4E (0.41) | KDM4EDHODH | |
| SCHEMBL10074512 | 0.88 | PIK3R1 (0.42) | KDM4EDHODH | |
| SCHEMBL10074518 | 0.87 | ALDH1A1 (0.39) | KDM4EDHFRMEN1KMT2A | |
| SCHEMBL10074513 | 0.85 | TOP1 (0.43) | KDM4EHTTRXFP1DHODH | |
| SCHEMBL1755017 | 0.85 | KDM4E (0.44) | KDM4EMEN1PKMKMT2ADHODH | |
| SCHEMBL10074712 | 0.85 | PIK3R1 (0.36) | KDM4EMEN1PKMHTTRAB9A | |
| SCHEMBL1755014 | 0.85 | KDM4E (0.44) | KDM4EMEN1PKMKMT2ADHODH | |
| SCHEMBL10050465 | 0.84 | KDM4E (0.46) | KDM4EDHFRTYMSDHODH | |
| SCHEMBL1754982 | 0.83 | ALDH1A1 (0.38) | KDM4EMEN1PKMHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119828-B2 | Material for an organic electroluminescence device and an organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | AFF4, KCNH3, HCN4 | KDM4E 573/4885DHFR 3591/4885TYMS 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.