Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078259 | 1.00 | SYK (0.37) | SYKCTSSPSMB1CTRB1CTSL | |
| SCHEMBL10074471 | 1.00 | SYK (0.37) | SYKCTSSPSMB1CTRB1CTSL | |
| SCHEMBL10077384 | 0.93 | REN (0.34) | CTSSPSMB1CTSBRENADRB2 | |
| SCHEMBL10074997 | 0.92 | PSMB1 (0.38) | SYKCTSSPSMB1CTRB1CTSL | |
| SCHEMBL10074153 | 0.92 | PSMB1 (0.38) | SYKCTSSPSMB1CTRB1CTSL | |
| SCHEMBL10074716 | 0.89 | REN (0.37) | CTSSPSMB1CTSBRENADRB2 | |
| SCHEMBL10074129 | 0.89 | REN (0.37) | CTSSPSMB1CTSBRENADRB2 | |
| SCHEMBL10078267 | 0.89 | REN (0.37) | CTSSPSMB1CTSBRENADRB2 | |
| SCHEMBL10074727 | 0.88 | SYK (0.42) | SYKCTSSPSMB1RENCTSK | |
| SCHEMBL10078394 | 0.88 | SYK (0.42) | SYKCTSSPSMB1RENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418196-A1 | Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors | IMTM GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |