Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17193149 | 0.94 | TLR2 (0.52) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL12917711 | 0.93 | TLR2 (0.54) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL12072047 | 0.93 | TLR2 (0.54) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL13058948 | 0.93 | TLR2 (0.49) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL13652764 | 0.92 | TLR2 (0.49) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL9755158 | 0.91 | KMT2A (0.62) | TLR2CASP3KMT2A | |
| SCHEMBL27577299 | 0.90 | KMT2A (0.53) | TLR2CASP3KMT2AEPHX2 | |
| SCHEMBL30353581 | 0.90 | CASP3 (0.55) | TLR2CASP3KMT2A | |
| SCHEMBL28413990 | 0.90 | CASP3 (0.55) | TLR2CASP3KMT2A | |
| SCHEMBL28413987 | 0.89 | TLR2 (0.51) | TLR2CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | UNIVERSITE DE MONTREAL (CA) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101257-A1 | PROCESSES FOR PREPARING AMINO-SUBSTITUTED GAMMA-LACTAMS | QPCT, GLUL, ASNS | TLR2 4462/4885CASP3 4203/4885KMT2A 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.