Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.45 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487237 | 0.83 | NOD1 (0.51) | NOD1PIN1CA2CYP2C9SLC6A5 | |
| SCHEMBL2487239 | 0.83 | NOD1 (0.51) | NOD1PIN1CA2CYP2C9SLC6A5 | |
| SCHEMBL3787753 | 0.81 | KDM4E (0.52) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 | |
| SCHEMBL3786186 | 0.81 | KDM4E (0.52) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 | |
| SCHEMBL7439465 | 0.81 | KDM4E (0.52) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 | |
| SCHEMBL9831561 | 0.79 | NOD1 (0.62) | NOD1CA2SLC6A5HDAC2 | |
| SCHEMBL6668178 | 0.79 | NOD1 (0.62) | NOD1CA2SLC6A5HDAC2 | |
| SCHEMBL2708048 | 0.79 | TGFBR1 (0.41) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 | |
| SCHEMBL2707933 | 0.79 | TGFBR1 (0.41) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 | |
| SCHEMBL203913 | 0.79 | TGFBR1 (0.41) | PLA2G2CTSHRALDH1A1KMT2AFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093231-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | TELIK, INC. | 2008-02-14 | — | — | US | disclosed |
| US-7262182-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | MTAP, TYMP, PHOSPHO1 | NOD1 2022/4885PLA2G2C 1228/4885PIN1 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.