Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24108521 | 1.00 | ITGB3 (0.39) | ITGB3ITGA2BITGAVTGFBR1KDM4E | |
| SCHEMBL7416802 | 0.83 | HDAC1 (0.43) | ITGB3ITGA2BITGAVTGFBR1MMP2 | |
| SCHEMBL7416795 | 0.83 | HDAC1 (0.43) | ITGB3ITGA2BITGAVTGFBR1MMP2 | |
| SCHEMBL16478583 | 0.82 | USP2 (0.33) | ITGB3ITGA2BUSP2TSHRMMP2 | |
| SCHEMBL12863144 | 0.82 | TGFBR1 (0.48) | ITGB3ITGA2BITGAVTGFBR1KDM4E | |
| SCHEMBL27621241 | 0.82 | TGFBR1 (0.48) | ITGB3ITGA2BITGAVTGFBR1KDM4E | |
| SCHEMBL3528855 | 0.82 | TGFBR1 (0.48) | ITGB3ITGA2BITGAVTGFBR1KDM4E | |
| Hydrochloric Acid SCHEMBL32662559 | 0.81 | HDAC1 (0.41) | ITGB3ITGA2BITGAVTGFBR1MMP2 | |
| SCHEMBL12071190 | 0.80 | SCN9A (0.34) | ITGB3ITGA2BCYP2C19USP2TSHR | |
| SCHEMBL12069014 | 0.80 | SCN9A (0.34) | ITGB3ITGA2BCYP2C19USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150368213-A1 | Novel Inhibitors of System Xc- | THE UNIVERSITY OF MONTANA | 2015-12-24 | — | — | US | disclosed |
| US-8093231-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | TELIK, INC. | 2008-02-14 | — | — | US | disclosed |
| US-7262182-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | MTAP, TYMP, PHOSPHO1 | ITGB3 3636/4885ITGA2B 4057/4885ITGAV 3851/4885 |
| US-20150368213-A1 | Novel Inhibitors of System Xc- | SLC7A11, SLC1A1, SLC1A2 | ITGB3 3756/4885ITGA2B 3877/4885ITGAV 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.