Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.74 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ULK1 | O75385 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RHOA | P61586 | 1/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073044 | 0.88 | F10 (0.59) | SMN1; SMN2F10AURKAAURKBALOX15 | |
| SCHEMBL10076298 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2F10AURKAAURKBALOX15 | |
| SCHEMBL21240932 | 0.86 | SMN1; SMN2 (0.94) | SMN1; SMN2MAPTMEN1KMT2ATDP1 | |
| SCHEMBL20425994 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2F10AURKAAURKBALOX15 | |
| SCHEMBL8298268 | 0.84 | SMN1; SMN2 (0.97) | SMN1; SMN2MAPTMEN1KMT2ATDP1 | |
| SCHEMBL259381 | 0.84 | NPSR1 (0.72) | SMN1; SMN2F10ALOX15ULK1KHK | |
| SCHEMBL18774005 | 0.83 | SMN1; SMN2 (0.89) | SMN1; SMN2MAPTMEN1KMT2ATDP1 | |
| SCHEMBL2449231 | 0.81 | F10 (0.56) | SMN1; SMN2F10ALOX15ULK1MAPT | |
| SCHEMBL2452221 | 0.81 | F10 (0.56) | SMN1; SMN2F10ALOX15ULK1MEN1 | |
| SCHEMBL24016844 | 0.81 | RXFP1 (0.59) | SMN1; SMN2F10ALOX15ULK1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093231-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | TELIK, INC. | 2008-02-14 | — | — | US | disclosed |
| US-7262182-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | MTAP, TYMP, PHOSPHO1 | SMN1; SMN2 1097/4885F10 4075/4885AURKA 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.