Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | ULK1 | O75385 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19408118 | 0.86 | MEN1 (0.69) | F10ULK1KMT2AMEN1LMNA | |
| SCHEMBL1446580 | 0.85 | MGLL (0.58) | KMT2AMEN1ALPLALPIALPG | |
| SCHEMBL2452221 | 0.84 | F10 (0.56) | F10ULK1KMT2AMEN1NPC1 | |
| SCHEMBL259381 | 0.84 | NPSR1 (0.72) | F10ULK1LMNANPC1TSHR | |
| SCHEMBL2451482 | 0.83 | ULK1 (0.56) | ULK1NPC1RAB9AHTT | |
| SCHEMBL1318166 | 0.83 | HPGD (0.66) | F10ULK1KMT2AMEN1LMNA | |
| SCHEMBL2246607 | 0.83 | MEN1 (0.69) | KMT2AMEN1LMNANPC1EPHX1 | |
| SCHEMBL2446479 | 0.83 | HPGD (0.66) | F10ULK1KMT2AMEN1LMNA | |
| SCHEMBL1318173 | 0.83 | HPGD (0.66) | F10ULK1KMT2AMEN1LMNA | |
| SCHEMBL31442189 | 0.82 | RXFP1 (0.58) | F10ULK1ALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |