SCHEMBL10076310

SCHEMBL10076310

Cc1cc(C#N)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)C(F)(F)F)nn1-c1ccccc1Cl

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 10/20 0.33
SLC2A3 P11169 10/20 0.33
SLC2A4 P14672 10/20 0.33
SLC2A2 P11168 5/20 0.32
GCK P35557 1/20 0.31
KCNH2 Q12809 1/20 0.31
DHODH Q02127 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10076315 0.95 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2GCK
SCHEMBL10076312 0.93 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL10076318 0.92 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL10083276 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2GCK
SCHEMBL12052429 0.90 GCK (0.33) SLC2A1SLC2A3SLC2A4SLC2A2GCK
SCHEMBL12052426 0.89 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL10076309 0.88 SLC2A1 (0.32) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL10076317 0.87 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2MEN1
SCHEMBL13085513 0.86 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2GCK
SCHEMBL13085494 0.86 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 US disclosed
WO-2012010525-A2 USE OF ANTHRANILIC ACID AMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY WATERING, MIXING WITH SOIL, DRENCH TREATMENT, DROPLET APPLICATION, INJECTION INTO THE SOIL, STEMS OR BLOSSOMS, IN HYDROPONIC SYSTEMS, BY TREATING THE PLANTING HOLE OR IMMERSION APPLICATION, FLOATING OR SEED BOX APPLICATION OR BY THE TREATMENT OF SEEDS, AND FOR INCREASING THE STRESS TOLERANCE IN PLANTS TO ABIOTIC STRESS BAYER CROPSCIENCE AG (DE) 2012-01-26 WO disclosed
US-20120010073-A1 Anthranilamides in combination with fungicides BAYER CROPSCIENCE AG (DE) 2012-01-12 US disclosed
WO-2012004221-A2 ANTHRANILAMIDES IN COMBINATION WITH FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-01-12 WO disclosed
WO-2011157778-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010073-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 SLC2A1 4485/4885SLC2A3 4386/4885SLC2A4 4434/4885
US-20120022112-A1 USE OF ANTHRANILAMIDE DERIVATIVES FOR CONTROLLING INSECTS AND SPIDER MITES BY DRENCHING, SOIL MIXING, FURROW TREATMENT, DRIP APPLICATION, SOIL, STEM OR FLOWER INJECTION, IN HYDROPONIC SYSTEMS, BY PLANTING HOLE TREATMENT OR DIP APPLICATION, FLOATING OR SEEDBOX APPLICATION OR BY TREATING SEED, AND ALSO FOR ENHANCING THE STRESS TOLERANCE OF PLANTS TO ABIOTIC STRESS CDY1; CDY1B, DHX9, DHX29 SLC2A1 2970/4885SLC2A3 2492/4885SLC2A4 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.