Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076574 | 0.88 | OGA (0.63) | OGAKDM4ENPSR1MAPTALDH1A1 | |
| SCHEMBL6131981 | 0.79 | OGA (0.61) | OGAKDM4ENPSR1PANK3ADRB2 | |
| SCHEMBL17551302 | 0.79 | OGA (1.00) | OGA | |
| SCHEMBL1423658 | 0.78 | HRH3 (0.60) | OGAKDM4ENPSR1NPC1GAA | |
| SCHEMBL6131879 | 0.77 | OGA (0.59) | OGAKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL6131851 | 0.77 | OGA (0.59) | OGAKDM4ENPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7690290 | 0.77 | OGA (0.59) | OGAKDM4ENPSR1PANK3ADRB2 | |
| Hydrochloric Acid SCHEMBL7690292 | 0.77 | OGA (0.59) | OGAKDM4ENPSR1PANK3ADRB2 | |
| SCHEMBL10053134 | 0.76 | POLB (0.58) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6131897 | 0.76 | OGA (0.58) | OGAKDM4ENPSR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |