Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076572 | 0.88 | OGA (0.65) | OGAALDH1A1KDM4ENPSR1MAPT | |
| SCHEMBL17551302 | 0.78 | OGA (1.00) | OGA | |
| SCHEMBL6131981 | 0.78 | OGA (0.61) | OGAKDM4ENPSR1DRD2DRD3 | |
| SCHEMBL1423658 | 0.77 | HRH3 (0.60) | OGAALDH1A1KDM4ENPSR1POLB | |
| Hydrochloric Acid SCHEMBL7690290 | 0.76 | OGA (0.59) | OGAKDM4ENPSR1DRD2DRD3 | |
| SCHEMBL6131879 | 0.76 | OGA (0.59) | OGAALDH1A1HPGDKDM4ENPSR1 | |
| Hydrochloric Acid SCHEMBL7690292 | 0.76 | OGA (0.59) | OGAKDM4ENPSR1DRD2DRD3 | |
| SCHEMBL6131851 | 0.76 | OGA (0.59) | OGAALDH1A1HPGDKDM4ENPSR1 | |
| SCHEMBL15830258 | 0.75 | MC4R (0.66) | OGAKCNH2ACHEDRD3MAPT | |
| Hydrochloric Acid SCHEMBL6131897 | 0.75 | OGA (0.58) | OGAALDH1A1HPGDKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |