Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CDA | P32320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547466 | 0.90 | NPSR1 (0.33) | L3MBTL1KMT2A | |
| SCHEMBL12449420 | 0.87 | ALDH1A1 (0.34) | L3MBTL1KMT2A | |
| SCHEMBL17050171 | 0.75 | ALDH1A1 (0.33) | L3MBTL1KMT2A | |
| SCHEMBL18571360 | 0.74 | — | — | |
| SCHEMBL8280285 | 0.71 | ACE (0.43) | — | |
| SCHEMBL8278544 | 0.71 | — | — | |
| SCHEMBL24983126 | 0.70 | — | — | |
| SCHEMBL17037252 | 0.70 | — | — | |
| SCHEMBL8277265 | 0.69 | L3MBTL1 (0.39) | L3MBTL1KMT2A | |
| SCHEMBL8280295 | 0.68 | ACE (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468744-A2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-27 | — | — | EP | disclosed |
| EP-2311851-A2 | Inhibitors of serine proteases, particularly HCV NS3-NS4A protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-20 | — | — | EP | disclosed |