Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628423 | 0.82 | PARP10 (0.42) | PARP10PARP1KMT2AMEN1MAPT | |
| SCHEMBL31470006 | 0.76 | MAPT (0.49) | PARP10PARP1KMT2AMEN1MAPT | |
| SCHEMBL5230478 | 0.73 | BRPF1 (0.69) | PARP10PARP1KMT2AMEN1MAPT | |
| SCHEMBL31020734 | 0.72 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL14288738 | 0.71 | MAPT (0.44) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL12894753 | 0.71 | PARP10 (0.58) | PARP10PARP1KMT2AMEN1MAPT | |
| SCHEMBL11425719 | 0.70 | PARP10 (0.41) | PARP10PARP1KMT2AMEN1MAPT | |
| SCHEMBL2632664 | 0.70 | KIF11 (0.54) | PARP10PARP1KIF11 | |
| SCHEMBL4991137 | 0.70 | PARP10 (0.56) | PARP10PARP1GAAARKIF11 | |
| SCHEMBL11419524 | 0.69 | MEN1 (0.51) | KMT2AMEN1MAPTALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418213-A1 | NEUROMEDIN U DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-02-15 | — | — | EP | disclosed |