Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078102 | 0.92 | PPARA (0.60) | PPARAPPARDFFAR1PPARG | |
| SCHEMBL2912655 | 0.86 | FFAR1 (0.54) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL222201 | 0.85 | FFAR1 (0.63) | FFAR1 | |
| SCHEMBL10077142 | 0.83 | FFAR1 (0.50) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL10078105 | 0.82 | FFAR1 (0.51) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL10078109 | 0.82 | FFAR1 (0.51) | PPARAPPARDFFAR1FFAR4PPARG | |
| SCHEMBL2890248 | 0.79 | FFAR1 (0.53) | PPARAPPARDFFAR1FFAR4 | |
| SCHEMBL2920491 | 0.79 | KDM4E (0.54) | PPARAFFAR1FFAR4PPARG | |
| SCHEMBL10077712 | 0.79 | FFAR1 (0.47) | PPARAPPARDFFAR1FFAR4 | |
| SCHEMBL2921997 | 0.78 | FFAR1 (0.53) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |