Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 15/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.84 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302710 | 0.93 | GHSR (0.86) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL2742703 | 0.92 | GHSR (1.00) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL12584175 | 0.92 | GHSR (1.00) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL5791730 | 0.85 | GHSR (0.73) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL5794340 | 0.84 | GHSR (0.82) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL5794554 | 0.81 | CYP2D6 (0.90) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL21032843 | 0.81 | GHSR (0.87) | GHSRCYP2D6KCNH2 | |
| SCHEMBL5823255 | 0.81 | GHSR (0.80) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL5823257 | 0.81 | GHSR (0.80) | GHSRCYP2D6KCNH2CYP3A4 | |
| SCHEMBL10064690 | 0.80 | GHSR (1.00) | GHSRCYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |