⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264292 | 0.73 | — | — | |
| SCHEMBL2222528 | 0.72 | — | — | |
| SCHEMBL4879869 | 0.71 | — | — | |
| SCHEMBL4399070 | 0.71 | — | — | |
| SCHEMBL12338364 | 0.70 | — | — | |
| SCHEMBL8175602 | 0.68 | LMNA (0.34) | — | |
| SCHEMBL10703920 | 0.68 | — | — | |
| SCHEMBL4423508 | 0.68 | — | — | |
| SCHEMBL27510089 | 0.67 | — | — | |
| SCHEMBL8358420 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081922-B1 | 5,6-Ring annulated indole derivatives and use thereof | SCHERING CORP (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2008082484-A1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |