Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175597 | 0.75 | TSHR (0.32) | LMNATSHRALDH1A1HPGDHTT | |
| SCHEMBL10776085 | 0.69 | TSHR (0.32) | LMNATSHRALDH1A1HPGDHTT | |
| SCHEMBL4772240 | 0.69 | GLA (0.38) | LMNATSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10077299 | 0.68 | — | — | |
| SCHEMBL4399070 | 0.66 | — | — | |
| SCHEMBL8947546 | 0.64 | TSHR (0.48) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL28417053 | 0.64 | TSHR (0.48) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL4912716 | 0.64 | TSHR (0.40) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL13969442 | 0.63 | TSHR (0.42) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL819133 | 0.63 | TSHR (0.39) | LMNACYP1A2CYP3A4MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000044560-A | BENZOQUINOLIZINE DERIVATIVE AND ITS PRODUCTION | KYORIN PHARMACEUT CO LTD | 2000-02-15 | — | — | JP | disclosed |