SCHEMBL10077571

SCHEMBL10077571

CCCCCCCCCCCSSCCCCCCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 1/20 0.40
DGKA P23743 1/20 0.40
PRKCA P17252 6/20 0.39
NAAA Q02083 3/20 0.38
FAAH O00519 1/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19649646 0.97 KMT2A (0.47) KMT2ASMN1; SMN2GAADGKAPRKCA
SCHEMBL27398781 0.94 KMT2A (0.41) KMT2ASMN1; SMN2GAAPRKCANAAA
SCHEMBL19611483 0.93 SMN1; SMN2 (0.37) KMT2ASMN1; SMN2GAALMNA
SCHEMBL5580899 0.93 SMN1; SMN2 (0.37) KMT2ASMN1; SMN2GAALMNA
SCHEMBL2316237 0.93 SMN1; SMN2 (0.37) KMT2ASMN1; SMN2GAALMNA
SCHEMBL2772797 0.93 SMN1; SMN2 (0.37) KMT2ASMN1; SMN2GAALMNA
SCHEMBL4749529 0.91 KMT2A (0.54) KMT2ASMN1; SMN2DGKAPRKCANAAA
SCHEMBL18218758 0.91 KMT2A (0.54) KMT2ASMN1; SMN2DGKAPRKCANAAA
SCHEMBL1361856 0.91 KMT2A (0.54) KMT2ASMN1; SMN2DGKAPRKCANAAA
SCHEMBL337170 0.91 KMT2A (0.54) KMT2ASMN1; SMN2DGKAPRKCANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9340567-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2016-05-17 US disclosed
US-9340567-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2016-05-17 US disclosed
US-20150198552-A9 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2015-07-16 US disclosed
US-20150198552-A9 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2015-07-16 US disclosed
US-8951400-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2015-02-10 US disclosed
US-8951400-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2015-02-10 US disclosed
US-20140311922-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2014-10-23 US disclosed
US-20140311922-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2014-10-23 US disclosed
US-8734631-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2014-05-27 US disclosed
US-8734631-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2014-05-27 US disclosed
WO-2013067349-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-10 WO disclosed
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-09 US disclosed
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-09 US disclosed
WO-2012012537-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-26 WO disclosed
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-19 US disclosed
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-19 US disclosed
US-20090253149-A1 Novel Chemistry Used in Biosensors OHMX CORPORATION (US) 2009-10-08 US disclosed
US-20090253149-A1 Novel Chemistry Used in Biosensors OHMX CORPORATION (US) 2009-10-08 US disclosed
WO-2009052436-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2009-04-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS SSBP1, OSGEP, OCIAD2 KMT2A 4485/4885SMN1; SMN2 4513/4885GAA 3787/4885
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS GPX1, GPX4, FECH KMT2A 3760/4885SMN1; SMN2 4729/4885GAA 3365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.