Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569873 | 0.83 | ALOX15 (0.42) | ALOX15ALOX12BACE1NPC1MAPT | |
| SCHEMBL2563485 | 0.83 | ALOX15 (0.46) | ALOX15ALOX12BACE1NPC1MAPT | |
| SCHEMBL13673358 | 0.82 | ALOX15 (0.41) | ALOX15ALOX12BACE1NPC1 | |
| SCHEMBL10042946 | 0.82 | ALOX15 (0.41) | ALOX15ALOX12BACE1NPC1 | |
| SCHEMBL2570965 | 0.81 | ALOX15 (0.40) | ALOX15ALOX12BACE1MAPT | |
| SCHEMBL2563436 | 0.81 | ALOX15 (0.40) | ALOX15ALOX12BACE1MAPTMAPK1 | |
| SCHEMBL2570309 | 0.80 | ALOX15 (0.43) | ALOX15ALOX12NPC1MAPT | |
| SCHEMBL2566790 | 0.80 | ALOX15 (0.39) | ALOX15ALOX12BACE1MAPT | |
| SCHEMBL2568812 | 0.79 | ALOX15 (0.38) | ALOX15ALOX12BACE1NPC1MAPT | |
| SCHEMBL10042943 | 0.78 | GAA (0.39) | ALOX15ALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407462-A1 | Substituted chroman derivatives, medicaments and use in therapy | Marshall Edwards, Inc. (US) | 2012-01-18 | — | — | EP | disclosed |