Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321304 | 0.88 | ALDH1A1 (0.54) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL1558360 | 0.87 | HTR2A (0.49) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL1732171 | 0.85 | HTR2A (0.47) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL10083723 | 0.85 | HTR2A (0.47) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL2034897 | 0.83 | GPR84 (0.51) | HTR2AGPR84FFAR1ALDH1A1GAA | |
| SCHEMBL14363141 | 0.81 | HTR2A (0.48) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL25678359 | 0.81 | HTR2A (0.47) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL23160620 | 0.81 | GPR84 (0.50) | HTR2AGPR84FFAR1ALDH1A1ATM | |
| SCHEMBL16234666 | 0.81 | PBRM1 (0.54) | HTR2AGPR84FFAR1IGF1RSRC | |
| SCHEMBL3721316 | 0.80 | GPR84 (0.49) | HTR2AGPR84ALDH1A1ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013170-B1 | 4-SQUARYLPIPERAZINE DERIVATIVES AS ANTIVIRAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2012-06-27 | — | — | EP | disclosed |