Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045598 | 0.93 | KCNH3 (0.41) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL24575756 | 0.91 | HDAC8 (0.42) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL902169 | 0.91 | HDAC8 (0.42) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL11049049 | 0.90 | MAPT (0.42) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL901094 | 0.87 | MAPT (0.37) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9572777 | 0.86 | MAPT (0.44) | MAPTALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL9572583 | 0.84 | MAPT (0.43) | MAPTALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL22392990 | 0.82 | L3MBTL1 (0.50) | MAPTALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28103284 | 0.82 | HDAC2 (0.37) | MAPTALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL489425 | 0.81 | MAPT (0.47) | MAPTALDH1A1TDP1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040853-A1 | GROUP 5 METAL COMPLEXES USEFUL FOR AMINE FUNCTIONALIZATION AND SYNTHETIC PROCESS FOR MANUFACTURE THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-04-05 | — | — | WO | disclosed |