Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | G6PD | P11413 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DAB2IP | Q5VWQ8 | 1/20 | 0.41 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924361 | 0.88 | ESR1 (0.67) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL6263461 | 0.88 | ESR1 (0.67) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL7517563 | 0.88 | ESR1 (0.67) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL15307736 | 0.85 | ESR1 (0.48) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL14423904 | 0.80 | ESR1 (0.77) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL23645783 | 0.79 | SHBG (0.53) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL23628430 | 0.79 | ESR1 (0.43) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL15301468 | 0.77 | ESR1 (0.41) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL10079782 | 0.77 | ESR1 (0.41) | ESR1ESR2LMNAMEN1MAPT | |
| SCHEMBL7624080 | 0.77 | ESR1 (0.53) | ESR1ESR2LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051988-A2 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-04-26 | — | — | WO | disclosed |