Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31557722 | 0.85 | OPRL1 (0.62) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL10057650 | 0.84 | OPRL1 (0.63) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL18029400 | 0.84 | OPRL1 (0.70) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL26706222 | 0.82 | OPRL1 (0.59) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL30227020 | 0.82 | OPRL1 (0.59) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL10640602 | 0.82 | SLC6A2 (0.48) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL10638058 | 0.81 | LMNA (0.46) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL28796806 | 0.81 | OPRM1 (0.60) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL2925749 | 0.81 | OPRM1 (0.63) | OPRL1OPRM1OPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL18767237 | 0.81 | OPRL1 (0.61) | OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148404-B2 | Modulators of CB1 receptors | 7TM PHARMA A/S (DK) | 2012-04-03 | — | — | US | disclosed |
| US-20100144701-A1 | Modulators of CB1 Receptors | 7TM PHARMA A/S (DK) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144701-A1 | Modulators of CB1 Receptors | CNR1, CNR2, GPR6 | OPRL1 23/4885OPRM1 81/4885OPRD1 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.